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Dipl.-Biol. Dr. rer. nat

Christine Cirl

European Patent Attorney, European Trade Mark and Design Attorney, Patent Attorney (Germany)
Location: Munich
Tel +49 89 549075-0
Fax +49 89 55027555
Christine Cirl

Studied Biology with focus on Technical Biology at Technical University (TU) Munich, Max-Planck Institute for Biochemistry, Munich, and at GSF (Helmholtz Center Munich, department: Gene vectors), specializing on Rational Protein Engineering; post-gradual studies and PhD (Dr. rer. nat.) and PostDoc at Institute for Medical Microbiology, Immunology and Hygiene, TU Munich; professional experience in the (re)insurance business (MunichRe and Allianz; areas: risk management, sustainability, due-diligence).

Legal training at an international law firm with accompanying legal studies at the Distance-Learning University of Hagen, at the German Patent and Trademark Office and the Federal Patent Court in Munich. Patent Attorney (Germany) since 2014, European Patent Attorney since 2015. At Eisenführ Speiser since 2015.

In her role as patent attorney, Christine Cirl supports clients in the field of pharmaceutical, industrial and plant biotechnology, immunology, biochemistry and microbiology as well as food and organic chemistry. She has professional experience in drafting, prosecuting and enforcing German, European and international intellectual property rights, including opposition proceedings, as well as in preparing legal opinions and in providing extensive and client-specific search strategies within the scope of FTO analyses.

Languages: German, English, French and Japanese (basics)

Memberships: Patent Attorneys Association (PAK), Institute of Professional Representatives before the European Patent Office (epi), Society for Biochemistry and Molecular Biology (GBM)

Publications / Presentations

  • Christine Cirl, Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation, J. Clin. Invest, 126(7):2425-36, 2016 Jul. 1. Weitere Autoren/Further authors: Waldhuber A., Puthia M., Wieser A, Dürr S., Neumann-Pfeifer S., Albrecht S.
  • Christine Cirl, Katrin Winkelmann, Beitrag zum Tagungsband sowie Vortrag zum Thema "Analyse von Patentportfolios: Generierung aussagekräftiger Ergebnisse als Entscheidungshilfe für die strategische Planung" im Rahmen der PATINFO 2016 "Big Data - Chancen und Herausforderungen", 8. bis 10. Juni 2016, Ilmenau
  • Christine Cirl, A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli, Pathogens, 5(1): pii: E25, 2016 Feb. 29. Weitere Autoren/Further authors: Waldhuber A., Snyder G.A.
  • Christine Cirl, Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry, J. Biol. Chem., 2014, Jan. 10, 289(2), 669-79. Weitere Autoren/Further authors: Snyder, G.A., Deredge, D., Waldhuber, A., Fresquez, T., Wilkins, D.Z., Smith, P.T., Duerr, .S, Jiang, J., Jennings, W., Luchetti, T., Snyder, N., Sundberg, E.J., Wintrode, P., Miethke, T., Xiao, T.S.
  • Christine Cirl, Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic E. coli, PNAS, 2013, 110 (17), 6985-6990. Weitere Autoren/Further authors: Snyder, G. A., Jiang, J., Chen, K., Waldhuber, A., Smith, P., Römmler, F., Snyder, N., Fresquez, T., Dürr, S., Tjandra, N., Miethke, T., Xiao, T.S.
  • Christine Cirl, Toll-like receptors 2 and 4 regulate the frequency of IFNγ-producing CD4+ T-cells during pulmonary infection with Chlamydia pneumoniae, PLoS One, 2011, e26101. Weitere Autoren/Further authors: Wantia, N., Rodriguez, N., Ertl, T., Dürr, S., Layland, L.E., Wagner, H., Miethke, T.
  • Christine Cirl, Structural studies of Toll like receptor signalling adaptors, Journal of Immunology, 2010, 134, 136.45. Weitere Autoren/Further authors: Snyder, G., Jiang, J., Chen, K., Fresquez, T., Smith, P., Snyder, N., Luchetti, T., Miethke, M., Tjandra, N., Xiao, T.
  • Christine Cirl, Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence, PLoS Pathogens, 26 (9), e1001120. Weitere Autoren/Further authors: Yadav, M., Zhang, J., Fischer, H., Huang, W., Lutay, N., Lum, J., Miethke, T., Svanborg, C.
  • Christine Cirl, Microbial Toll/Interleukin-1 receptor proteins: a new class of virulence factors, 300 (6), 396-401. Weiterer Autor/Further author: Miethke, T.
  • Christine Cirl, Chlamydophila pneumoniae downregulates MHC-class II expression by two cell type-specific mechanisms, Mol. Microbiol., 76 (3), 648-661. Weitere Autoren/Further authors: Peschel, G., Kernschmidt, L., Cirl, C., Wantia, N., Ertl, T., Dürr, S., Wagner, H., Miethke, T., Rodríguez, N.
  • Christine Cirl, Induction of iNOS by Chlamydophila pneumoniae requires MyD88-dependent activation of JNK, J. Leukoc. Biol. 84 (6), 1585-1593. Weitere Autoren/Further authors: Rodriguez, N., Lang, R., Wantia, N., Ertl, T., Dürr, S., Wagner, H., Miethke, T.
  • Christine Cirl, Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins, Nature Medicine, 14 (4), 399-406. Weitere Autoren/Further authors: Wieser, A., Yadav, M., Duerr, S., Schubert, S., Fischer, H., Stappert, D., Wantia, N., Rodriguez, N., Wagner, H., Svanborg, C., Miethke, T.